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Cross-reactive and pre-existing antibodies to therapeutic antibodies—Effects on treatment and immunogenicity
The potential for immunogenicity is an ever-present concern during the development of biopharmaceuticals. Therapeutic antibodies occasionally elicit an antibody response in patients, which can result in loss of response or adverse effects. However, antibodies that bind a drug are sometimes found in...
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| Veröffentlicht in: | MAbs |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4623040/ https://ncbi.nlm.nih.gov/pubmed/25962087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1048411 |
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