PTCH 1 staining of pancreatic neuroendocrine tumor (PNET) samples from patients with and without multiple endocrine neoplasia (MEN-1) syndrome reveals a potential therapeutic target

Pancreatic neuroendocrine tumors (PNETs) are rare, indolent tumors that may occur sporadically or develop in association with well-recognized hereditary syndromes, particularly multiple endocrine neoplasia type 1 (MEN-1). We previously demonstrated that the hedgehog (HH) signaling pathway was aberra...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Gurung, Buddha, Hua, Xianxin, Runske, Melissa, Bennett, Bonita, LiVolsi, Virginia, Roses, Robert, Fraker, Douglas A, Metz, David C
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Clinical Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623013/
https://ncbi.nlm.nih.gov/pubmed/25482929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.987574
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