Blocking M2 muscarinic receptor signaling inhibits tumor growth and reverses epithelial-mesenchymal transition (EMT) in non-small cell lung cancer (NSCLC)

Lung cancers express non-neuronal, cholinergic autoparacrine loop, which facilitates tumor growth. Interruption of M3 muscarinic cholinergic signaling has been reported to inhibit small cell lung cancer (SCLC) growth. The purpose of this study is to investigate if blocking autoparacrine muscarinic c...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Zhao, Qingnan, Gu, Xiajing, Zhang, Chun, Lu, Qin, Chen, Hongzhuan, Xu, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622973/
https://ncbi.nlm.nih.gov/pubmed/25778781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1029835
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