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Modulation of Kupffer cells on hepatic drug metabolism

AIM: To observe the effects of Kupffer cells on hepatic drug metabolic enzymes. METHODS: Kunming mice were ip injected with GdCl(3)10, 20, 40 mg/kg to decrease the number and block the function of kupffer cells selectively. The contents of drug metabolic enzymes, cytochrome P450, NADPH-cytochrom C r...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Ding, Hong, Tong, Jing, Wu, Shi-Cheng, Yin, Deng-Ke, Yuan, Xian-Fen, Wu, Jian-Yuan, Chen, Jun, Shi, Gang-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622775/
https://ncbi.nlm.nih.gov/pubmed/15112351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i9.1325
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