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Association of low p16INK4a and p15INK4b mRNAs expression with their CpG islands methylation with human hepatocellular carcinogenesis
AIM: To study the significance of p16 and p15 transcription suppression with hypermethylation of their genes’ 5’CpG islands during human hepatocellular carcinogenesis. METHODS: The mRNA expression levels of p16 and p15 genes were evaluated in cancerous, para-cancerous and non-cancerous tissues of 20...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622765/ https://ncbi.nlm.nih.gov/pubmed/15112341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i9.1276 |
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