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The interplay between DNA repair and autophagy in cancer therapy

DNA is the prime target of anticancer treatments. DNA damage triggers a series of signaling cascades promoting cellular survival, including DNA repair, cell cycle arrest, and autophagy. The elevated basal and/or stressful levels of both DNA repair and autophagy observed in tumor cells, in contrast t...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Zhang, Dan, Tang, Bo, Xie, Xia, Xiao, Yu-Feng, Yang, Shi-Ming, Zhang, Jian-Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622693/
https://ncbi.nlm.nih.gov/pubmed/25985143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1046022
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