Adaptation of the targeted capture Methyl-Seq platform for the mouse genome identifies novel tissue-specific DNA methylation patterns of genes involved in neurodevelopment

Methyl-Seq was recently developed as a targeted approach to assess DNA methylation (DNAm) at a genome-wide level in human. We adapted it for mouse and sought to examine DNAm differences across liver and 2 brain regions: cortex and hippocampus. A custom hybridization array was designed to isolate 99...

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Publicat a:Epigenetics
Autors principals: Hing, Benjamin, Ramos, Enrique, Braun, Patricia, McKane, Melissa, Jancic, Dubravka, Tamashiro, Kellie L K, Lee, Richard S, Michaelson, Jacob J, Druley, Todd E, Potash, James B
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622595/
https://ncbi.nlm.nih.gov/pubmed/25985232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2015.1045179
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