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Targeting of two aspects of metabolism in breast cancer treatment

Deregulated metabolism is gaining recognition as a hallmark of cancer cells, and is being explored for therapeutic potential. The Warburg effect is a metabolic phenotype that occurs in 90% of tumors, where glycolysis is favored despite the presence of oxygen. Dichloroacetate (DCA) is a pyruvate dehy...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Biol Ther
Asıl Yazarlar: Gang, Bevan P, Dilda, Pierre J, Hogg, Phillip J, Blackburn, Anneke C
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622508/
https://ncbi.nlm.nih.gov/pubmed/25482950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.955992
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