Glutathione-degradable drug-loaded nanogel effectively and securely suppresses hepatoma in mouse model

The reduction-responsive polymeric nanocarriers have attracted considerable interest because of a significantly higher concentration of intracellular glutathione in comparison with that outside cells. The smart nanovehicles can selectively transport the antitumor drugs into cells to improve efficaci...

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Bibliografiske detaljer
Udgivet i:Int J Nanomedicine
Main Authors: Liu, Xingang, Wang, Jianmeng, Xu, Weiguo, Ding, Jianxun, Shi, Bo, Huang, Kexin, Zhuang, Xiuli, Chen, Xuesi
Format: Artigo
Sprog:Inglês
Udgivet: Dove Medical Press 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622485/
https://ncbi.nlm.nih.gov/pubmed/26543363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S90000
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