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Molecular simulations study of novel 1,4-dihydropyridines derivatives with a high selectivity for Cav3.1 calcium channel

1,4-Dihydropyridines (DHPs) have been developed to treat hypertension, angina, and nerve system disease. They are thought to mainly target the L-type calcium channels, but low selectivity prompts them to block Cav1.2 and Cav3.1 channels simultaneously. Recently, some novel DHPs with different hydrop...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Protein Sci
मुख्य लेखकों: Liu, Xiaoguang, Yu, Hui, Zhao, Xi, Huang, Xu-Ri
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley & Sons, Ltd 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622207/
https://ncbi.nlm.nih.gov/pubmed/26256672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2763
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