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BET bromodomain inhibitors—A novel epigenetic approach in castration-resistant prostate cancer

The androgen receptor (AR) is central to the initiation and progression of prostate cancer, even after castration. There has been some success in therapies targeting AR signaling which have been shown to extend survival in men with castration-resistant prostate cancer (CRPC). However, durable respon...

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Foilsithe in:Cancer Biol Ther
Main Authors: Lochrin, Sarah E, Price, Douglas K, Figg, William D
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622075/
https://ncbi.nlm.nih.gov/pubmed/25535892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.962297
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