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BET bromodomain inhibitors—A novel epigenetic approach in castration-resistant prostate cancer

The androgen receptor (AR) is central to the initiation and progression of prostate cancer, even after castration. There has been some success in therapies targeting AR signaling which have been shown to extend survival in men with castration-resistant prostate cancer (CRPC). However, durable respon...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Lochrin, Sarah E, Price, Douglas K, Figg, William D
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622075/
https://ncbi.nlm.nih.gov/pubmed/25535892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384047.2014.962297
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