Endothelium Expression of Bcl-2 Is Essential for Normal and Pathological Ocular Vascularization

Bcl–2 is an anti-apoptotic protein with important roles in vascular homeostasis and angiogenesis. Mice globally lacking Bcl–2 (Bcl–2 -/-) are small in stature and succumb to renal failure shortly after weaning as a result of renal hypoplasia/cystic dysplasia. We have shown that Bcl–2 -/- mice displa...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zaitoun, Ismail S., Johnson, Ryan P., Jamali, Nasim, Almomani, Reem, Wang, Shoujian, Sheibani, Nader, Sorenson, Christine M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622043/
https://ncbi.nlm.nih.gov/pubmed/26444547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0139994
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