The sluggish-A gene of Drosophila melanogaster is expressed in the nervous system and encodes proline oxidase, a mitochondrial enzyme involved in glutamate biosynthesis.

Certain gene mutations in Drosophila melanogaster cause sluggish motor activity. We have localized the transcription unit of the sluggish-A gene to a 14.7-kb region at the base of the X chromosome and have cloned corresponding cDNAs. The predicted protein product has significant sequence similarity...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Hayward, D C, Delaney, S J, Campbell, H D, Ghysen, A, Benzer, S, Kasprzak, A B, Cotsell, J N, Young, I G, Miklos, G L
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1993
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8096642/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.7.2979
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