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α7 nicotinic ACh receptor‐deficient mice exhibit sustained attention impairments that are reversed by β2 nicotinic ACh receptor activation

BACKGROUND AND PURPOSE: Disruptions of executive function, including attentional deficits, are a hallmark of a number of diseases. ACh in the prefrontal cortex regulates attentive behaviour; however, the role of α7 nicotinic ACh receptor (α7nAChR) in attention is contentious. EXPERIMENTAL APPROACH:...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Kolisnyk, Benjamin, Al‐Onaizi, Mohammed A., Prado, Vania F., Prado, Marco A. M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621992/
https://ncbi.nlm.nih.gov/pubmed/26222090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13260
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