High EGFR and low p-Akt expression is associated with better outcome after nimotuzumab-containing treatment in esophageal cancer patients: preliminary clinical result and testable hypothesis

The epidermal growth factor receptor (EGFR) is widely overexpressed in esophageal squamous cell carcinoma (ESCC) and it results is associated with a poor prognosis. Identifying the subgroup of ESCC patients who are sensitive to EGFR-targeted therapy is a key point to facilitate its medical use. We r...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Chun-yu, Deng, Jia-ying, Cai, Xu-wei, Fu, Xiao-long, Li, Yuan, Zhou, Xiao-yan, Wu, Xiang-hua, Hu, Xi-chun, Fan, Min, Xiang, Jia-qing, Zhang, Ya-wei, Chen, Hai-quan, Perez, Rolando, Jiang, Guo-liang, Zhao, Kuai-le
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Clinical Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621919/
https://ncbi.nlm.nih.gov/pubmed/26124180
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