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Markedly Elevated Antibody Responses in Wild versus Captive Spotted Hyenas Show that Environmental and Ecological Factors Are Important Modulators of Immunity

Evolutionary processes have shaped the vertebrate immune system over time, but proximal mechanisms control the onset, duration, and intensity of immune responses. Based on testing of the hygiene hypothesis, it is now well known that microbial exposure is important for proper development and regulati...

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Bibliographic Details
Published in:PLoS One
Main Authors: Flies, Andrew S., Mansfield, Linda S., Grant, Chris K., Weldele, Mary L., Holekamp, Kay E.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621877/
https://ncbi.nlm.nih.gov/pubmed/26444876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137679
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