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Sleep disruption impairs hematopoietic stem cell transplantation in mice

Many of the factors affecting the success of hematopoietic cell transplantation are still unknown. Here we show in mice that donor’s sleep deprivation reduces the ability of its hematopoietic stem cells (HSCs) to engraft and reconstitute the blood and bone marrow of an irradiated recipient by more t...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Rolls, Asya, Pang, Wendy W., Ibarra, Ingrid, Colas, Damien, Bonnavion, Patricia, Korin, Ben, Heller, H. Craig, Weissman, Irving L., de Lecea, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621781/
https://ncbi.nlm.nih.gov/pubmed/26465715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9516
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