Copy number variations alter methylation and parallel IGF2 overexpression in adrenal tumors

Overexpression of insulin growth factor 2 (IGF2) is a hallmark of adrenocortical carcinomas and pheochromocytomas. Previous studies investigating the IGF2/H19 locus have mainly focused on a single molecular level such as genomic alterations or altered DNA methylation levels and the causal changes un...

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Bibliografski detalji
Izdano u:Endocr Relat Cancer
Glavni autori: Nielsen, Helene Myrtue, How-Kit, Alexandre, Guerin, Carole, Castinetti, Frederic, Vollan, Hans Kristian Moen, De Micco, Catherine, Daunay, Antoine, Taieb, David, Van Loo, Peter, Besse, Celine, Kristensen, Vessela N, Hansen, Lise Lotte, Barlier, Anne, Sebag, Frederic, Tost, Jörg
Format: Artigo
Jezik:Inglês
Izdano: Bioscientifica Ltd 2015
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621769/
https://ncbi.nlm.nih.gov/pubmed/26400872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-15-0086
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