Perioperative elafin for ischaemia-reperfusion injury during coronary artery bypass graft surgery: a randomised-controlled trial

BACKGROUND: Elafin is a potent endogenous neutrophil elastase inhibitor that protects against myocardial inflammation and injury in preclinical models of ischaemic-reperfusion injury. We investigated whether elafin could inhibit myocardial ischaemia-reperfusion injury induced during coronary artery...

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Detalhes bibliográficos
Publicado no:Heart
Main Authors: Alam, S R, Lewis, S C, Zamvar, V, Pessotto, R, Dweck, M R, Krishan, A, Goodman, K, Oatey, K, Harkess, R, Milne, L, Thomas, S, Mills, N M, Moore, C, Semple, S, Wiedow, O, Stirrat, C, Mirsadraee, S, Newby, D E, Henriksen, P A
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Coronary Artery Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621368/
https://ncbi.nlm.nih.gov/pubmed/26310261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/heartjnl-2015-307745
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