The D0 immunoglobulin-like domain plays a central role for the stronger binding of KIR3DL2 to B27 free heavy chain dimers

We have proposed that the killer cell immunoglobulin-like receptor KIR3DL2 binding more strongly to HLA-B27 (B27) β2m-free heavy chain (FHC) dimers regulates lymphocyte function in arthritis and infection. We compared the function of B27 FHC dimers with other class I heavy chains and identified cont...

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Bibliographic Details
Published in:J Immunol
Main Authors: Hatano, Hiroko, Shaw, Jacqueline, Marquardt, Kaitlin, Zhang, Zhiyong, Gauthier, Laurent, Chanteux, Stephanie, Rossi, Benjamin, Li, Demin, Mitchell, Julie, Kollnberger, Simon
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621334/
https://ncbi.nlm.nih.gov/pubmed/25582852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402214
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