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Propranolol Decreases Proliferation of Endothelial Cells Transformed by Kaposi's Sarcoma-Associated Herpesvirus and Induces Lytic Viral Gene Expression

Kaposi's sarcoma (KS) is common in Africa, but economic constraints hinder successful treatment in most patients. Propranolol, a generic β-adrenergic antagonist, decreased proliferation of KS-associated herpesvirus (KSHV)-infected cells. Downregulation of cyclin A2 and cyclin-dependent kinase 1...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: McAllister, Shane C., Hanson, Ryan S., Manion, Rory D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621132/
https://ncbi.nlm.nih.gov/pubmed/26269192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01569-15
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