Mechanisms of Dihydroartemisinin and Dihydroartemisinin/Holotransferrin Cytotoxicity in T-Cell Lymphoma Cells

The validated therapeutic effects of dihydroartemisinin (DHA) in solid tumors have encouraged us to explore its potential in treating T-cell lymphoma. We found that Jurkat cells (a T-cell lyphoma cell line) were sensitive to DHA treatment with a IC50 of dihydroartemisinin. The cytotoxic effect of DH...

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Udgivet i:PLoS One
Main Authors: Wang, Qiuyan, Wu, Shaoling, Zhao, Xindong, Zhao, Chunting, Zhao, Hongguo, Huo, Lanfen
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621048/
https://ncbi.nlm.nih.gov/pubmed/26502166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137331
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