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Micro Regional Heterogeneity of (64)Cu-ATSM and (18)F-FDG Uptake in Canine Soft Tissue Sarcomas: Relation to Cell Proliferation, Hypoxia and Glycolysis

OBJECTIVES: Tumour microenvironment heterogeneity is believed to play a key role in cancer progression and therapy resistance. However, little is known about micro regional distribution of hypoxia, glycolysis and proliferation in spontaneous solid tumours. The overall aim was simultaneous investigat...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Zornhagen, Kamilla Westarp, Hansen, Anders E., Oxboel, Jytte, Clemmensen, Andreas E., El Ali, Henrik H., Kristensen, Annemarie T., Kjær, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621038/
https://ncbi.nlm.nih.gov/pubmed/26501874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141379
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