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Targeting glutamine metabolism rescues mice from late-stage cerebral malaria
The most deadly complication of Plasmodium falciparum infection is cerebral malaria (CM) with a case fatality rate of 15–25% in African children despite effective antimalarial chemotherapy. There are no adjunctive treatments for CM, so there is an urgent need to identify new targets for therapy. Her...
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Pubblicato in: | Proc Natl Acad Sci U S A |
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Autori principali: | , , , , , , , , , , , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
National Academy of Sciences
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4620853/ https://ncbi.nlm.nih.gov/pubmed/26438846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516544112 |
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