Targeting glutamine metabolism rescues mice from late-stage cerebral malaria

The most deadly complication of Plasmodium falciparum infection is cerebral malaria (CM) with a case fatality rate of 15–25% in African children despite effective antimalarial chemotherapy. There are no adjunctive treatments for CM, so there is an urgent need to identify new targets for therapy. Her...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gordon, Emile B., Hart, Geoffrey T., Tran, Tuan M., Waisberg, Michael, Akkaya, Munir, Kim, Ann S., Hamilton, Sara E., Pena, Mirna, Yazew, Takele, Qi, Chen-Feng, Lee, Chen-Fang, Lo, Ying-Chun, Miller, Louis H., Powell, Jonathan D., Pierce, Susan K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620853/
https://ncbi.nlm.nih.gov/pubmed/26438846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516544112
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados