miR-143 Activation Regulates Smooth Muscle and Endothelial Cell Crosstalk in Pulmonary Arterial Hypertension

RATIONALE: The pathogenesis of PAH remains unclear. The four microRNAs representing the miR-143 and miR-145 stem loops are genomically clustered. OBJECTIVE: To elucidate the transcriptional regulation of the miR-143/145 cluster, and the role of miR-143 in PAH. METHODS AND RESULTS: We identified the...

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Bibliographic Details
Published in:Circ Res
Main Authors: Deng, Lin, Blanco, Francisco J., Stevens, Hannah, Lu, Ruifang, Caudrillier, Axelle, McBride, Martin, McClure, John D, Grant, Jenny, Thomas, Matthew, Frid, Maria, Stenmark, Kurt, White, Kevin, Seto, Anita G., Morrell, Nicholas W., Bradshaw, Angela C, MacLean, Margaret R., Baker, Andrew H.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620852/
https://ncbi.nlm.nih.gov/pubmed/26311719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.306806
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