X-ray structure determination using low-resolution electron microscopy maps for molecular replacement

Structures of multi-subunit macromolecular machines are primarily determined by either electron microscopy (EM) or X-ray crystallography. In many cases, a structure for a complex can be obtained at low resolution (at a coarse level of detail) with EM and at higher resolution (with finer detail) by X...

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Bibliographic Details
Published in:Nat Protoc
Main Authors: Jackson, Ryan N., McCoy, Airlie J., Terwilliger, Thomas C., Read, Randy J., Wiedenheft, Blake
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620705/
https://ncbi.nlm.nih.gov/pubmed/26226459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2015.069
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