Safety, Correlative Markers, and Clinical Results of Adjuvant Nivolumab in Combination with Vaccine in Resected High-Risk Metastatic Melanoma

PURPOSE: The anti-programmed death-1 (PD-1) antibody nivolumab (BMS-936558) has clinical activity in patients with metastatic melanoma. Nivolumab plus vaccine was investigated as adjuvant therapy in resected stage IIIC and IV melanoma patients. EXPERIMENTAL DESIGN: HLA-A*0201 positive patients with...

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Udgivet i:Clin Cancer Res
Main Authors: Gibney, Geoffrey T., Kudchadkar, Ragini R., DeConti, Ronald C., Thebeau, Melissa S., Czupryn, Maria P., Tetteh, Leticia, Eysmans, Cabell, Richards, Allison, Schell, Michael J., Fisher, Kate J., Horak, Christine E., Inzunza, H. David, Yu, Bin, Martinez, Alberto J., Younos, Ibrahim, Weber, Jeffrey S.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620684/
https://ncbi.nlm.nih.gov/pubmed/25524312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-2468
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