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Mechanisms of Cellular Proteostasis: Insights from Single-Molecule Approaches

Cells employ a variety of strategies to maintain proteome homeostasis. Beginning during protein biogenesis, the translation machinery and a number of molecular chaperones promote correct de novo folding of nascent proteins even before synthesis is complete. Another set of molecular chaperones helps...

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Bibliographic Details
Published in:Annu Rev Biophys
Main Authors: Bustamante, Carlos J., Kaiser, Christian M., Maillard, Rodrigo A., Goldman, Daniel H., Wilson, Christian A.M.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620553/
https://ncbi.nlm.nih.gov/pubmed/24895851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biophys-051013-022811
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