Dysregulation of Mitochondrial Functions and Osteogenic Differentiation in Cisd2-Deficient Murine Induced Pluripotent Stem Cells

Wolfram syndrome 2 (WFS2) is a premature aging syndrome caused by an irreversible mitochondria-mediated disorder. Cisd2, which regulates mitochondrial electron transport, has been recently identified as the causative gene of WFS2. The mouse Cisd2 knockout (KO) (Cisd2(−/−)) recapitulates most of the...

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Vydáno v:Stem Cells Dev
Hlavní autoři: Tsai, Ping-Hsing, Chien, Yueh, Chuang, Jen-Hua, Chou, Shih-Jie, Chien, Chian-Hsu, Lai, Ying-Hsiu, Li, Hsin-Yang, Ko, Yu-Lin, Chang, Yuh-Lih, Wang, Chen-Ying, Liu, Yung-Yang, Lee, Hsin-Chen, Yang, Chang-Hao, Tsai, Ting-Fen, Lee, Yi-Yen, Chiou, Shih-Hwa
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2015
Témata:
Original Research Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620525/
https://ncbi.nlm.nih.gov/pubmed/26230298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2015.0066
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