Knockout of Epstein-Barr Virus BPLF1 Retards B-Cell Transformation and Lymphoma Formation in Humanized Mice

BPLF1 of Epstein-Barr virus (EBV) is classified as a late lytic cycle protein but is also found in the viral tegument, suggesting its potential involvement at both initial and late stages of viral infection. BPLF1 possesses both deubiquitinating and deneddylating activity located in its N-terminal d...

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Publicado en:mBio
Autores principales: Whitehurst, Christopher B., Li, Guangming, Montgomery, Stephanie A., Montgomery, Nathan D., Su, Lishan, Pagano, Joseph S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620474/
https://ncbi.nlm.nih.gov/pubmed/26489865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01574-15
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