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Binding of Alphaherpesvirus Glycoprotein H to Surface α(4)β(1)-Integrins Activates Calcium-Signaling Pathways and Induces Phosphatidylserine Exposure on the Plasma Membrane

Intracellular signaling connected to integrin activation is known to induce cytoplasmic Ca(2+) release, which in turn mediates a number of downstream signals. The cellular entry pathways of two closely related alphaherpesviruses, equine herpesviruses 1 and 4 (EHV-1 and EHV-4), are differentially reg...

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Vydáno v:mBio
Hlavní autoři: Azab, Walid, Gramatica, Andrea, Herrmann, Andreas, Osterrieder, Nikolaus
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620472/
https://ncbi.nlm.nih.gov/pubmed/26489864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01552-15
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