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Polyploid Titan Cells Produce Haploid and Aneuploid Progeny To Promote Stress Adaptation

Cryptococcus neoformans is a major life-threatening fungal pathogen. In response to the stress of the host environment, C. neoformans produces large polyploid titan cells. Titan cell production enhances the virulence of C. neoformans, yet whether the polyploid aspect of titan cells is specifically i...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Gerstein, Aleeza C., Fu, Man Shun, Mukaremera, Liliane, Li, Zhongming, Ormerod, Kate L., Fraser, James A., Berman, Judith, Nielsen, Kirsten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620463/
https://ncbi.nlm.nih.gov/pubmed/26463162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01340-15
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