Screening and Identifying a Novel ssDNA Aptamer against Alpha-fetoprotein Using CE-SELEX

Alpha-fetoprotein (AFP) is a liver cancer associated protein and has long been utilized as a serum tumor biomarker of disease progression. AFP is usually detected in HCC patients by an antibody based system. Recently, however, aptamers generated from systematic evolution of ligands by exponential en...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Dong, Lili, Tan, Qiwen, Ye, Wei, Liu, Dongli, Chen, Haifeng, Hu, Hongwei, Wen, Duo, Liu, Yang, Cao, Ya, Kang, Jingwu, Fan, Jia, Guo, Wei, Wu, Weizhong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620443/
https://ncbi.nlm.nih.gov/pubmed/26497223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15552
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