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Environmental neurotoxin interaction with proteins: Dose-dependent increase of free and protein-associated BMAA (β-N-methylamino-L-alanine) in neonatal rat brain

β-Methylamino-L-alanine (BMAA) is implicated in the aetiology of neurodegenerative disorders. Neonatal exposure to BMAA induces cognitive impairments and progressive neurodegenerative changes including intracellular fibril formation in the hippocampus of adult rats. It is unclear why the neonatal hi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Karlsson, Oskar, Jiang, Liying, Ersson, Lisa, Malmström, Tim, Ilag, Leopold L., Brittebo, Eva B.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620439/
https://ncbi.nlm.nih.gov/pubmed/26498001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15570
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