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Cryptic relatedness in epidemiologic collections accessed for genetic association studies: experiences from the Epidemiologic Architecture for Genes Linked to Environment (EAGLE) study and the National Health and Nutrition Examination Surveys (NHANES)

Epidemiologic collections have been a major resource for genotype–phenotype studies of complex disease given their large sample size, racial/ethnic diversity, and breadth and depth of phenotypes, traits, and exposures. A major disadvantage of these collections is they often survey households and com...

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Pubblicato in:Front Genet
Autori principali: Malinowski, Jennifer, Goodloe, Robert, Brown-Gentry, Kristin, Crawford, Dana C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620157/
https://ncbi.nlm.nih.gov/pubmed/26579192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00317
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