FOXP3-microRNA-146-NF-κB axis and therapy for precancerous lesions in prostate

The tumor suppressive activity of FOXP3 has been observed in tumor initiation, but the underlying mechanism still remains largely unknown. Here, we identified a FOXP3-microRNA-146 (miR-146)-NF-κB axis in vitro and in vivo in prostate cancer cells. We observed that FOXP3 dramatically induced the expr...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Liu, Runhua, Yi, Bin, Wei, Shi, Yang, Wei-Hsiung, Hart, Karen M., Chauhan, Priyanka, Zhang, Wei, Mao, Xicheng, Liu, Xiuping, Liu, Chang-Gong, Wang, Lizhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620056/
https://ncbi.nlm.nih.gov/pubmed/25712341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2109
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