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Mutant human cells defective in induction of major histocompatibility complex class II genes by interferon gamma.

Using immunoselection, we have isolated 11 independent mutant HT1080 fibrosarcoma cell lines defective in the induction by interferon gamma (IFN-gamma) of the expression of the human leukocyte antigen HLA-DRA. The mutations are recessive and fall into five complementation groups. All the mutants are...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Mao, C, Davies, D, Kerr, I M, Stark, G R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46200/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8464903/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.7.2880
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