The Peptide Vaccine Combined with Prior Immunization of a Conventional Diphtheria-Tetanus Toxoid Vaccine Induced Amyloid β Binding Antibodies on Cynomolgus Monkeys and Guinea Pigs

The reduction of brain amyloid beta (Aβ) peptides by anti-Aβ antibodies is one of the possible therapies for Alzheimer's disease. We previously reported that the Aβ peptide vaccine including the T-cell epitope of diphtheria-tetanus combined toxoid (DT) induced anti-Aβ antibodies, and the prior...

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Publicado en:J Immunol Res
Main Authors: Yano, Akira, Ito, Kaori, Miwa, Yoshikatsu, Kanazawa, Yoshito, Chiba, Akiko, Iigo, Yutaka, Kashimoto, Yoshinori, Kanda, Akira, Murata, Shinji, Makino, Mitsuhiro
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619934/
https://ncbi.nlm.nih.gov/pubmed/26539559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/786501
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