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HENMT1 and piRNA Stability Are Required for Adult Male Germ Cell Transposon Repression and to Define the Spermatogenic Program in the Mouse
piRNAs are critical for transposable element (TE) repression and germ cell survival during the early phases of spermatogenesis, however, their role in adult germ cells and the relative importance of piRNA methylation is poorly defined in mammals. Using a mouse model of HEN methyltransferase 1 (HENMT...
Zapisane w:
Wydane w: | PLoS Genet |
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Główni autorzy: | , , , , , , , , , , , , , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Public Library of Science
2015
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619860/ https://ncbi.nlm.nih.gov/pubmed/26496356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005620 |
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