A Missense Mutation in the Transcription Factor ETV5 Leads to Sterility, Increased Embryonic and Perinatal Death, Postnatal Growth Restriction, Renal Asymmetry and Polydactyly in the Mouse

ETV5 (Ets variant gene 5) is a transcription factor that is required for fertility. In this study, we demonstrate that ETV5 plays additional roles in embryonic and postnatal developmental processes in the mouse. Through a genome-wide mouse mutagenesis approach, we generated a sterile mouse line that...

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Bibliografiske detaljer
Main Authors: Jamsai, Duangporn, Clark, Brett J., Smith, Stephanie J., Whittle, Belinda, Goodnow, Christopher C., Ormandy, Christopher J., O’Bryan, Moira K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804586/
https://ncbi.nlm.nih.gov/pubmed/24204802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077311
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