Involvement of Peripheral Nerves in the Transgenic PLP-α-Syn Model of Multiple System Atrophy: Extending the Phenotype

Multiple system atrophy (MSA) is a fatal, rapidly progressive neurodegenerative disease with (oligodendro-)glial cytoplasmic α-synuclein (α-syn) inclusions (GCIs). Peripheral neuropathies have been reported in up to 40% of MSA patients, the cause remaining unclear. In a transgenic MSA mouse model fe...

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Pubblicato in:PLoS One
Autori principali: Kuzdas-Wood, Daniela, Irschick, Regina, Theurl, Markus, Malsch, Philipp, Mair, Norbert, Mantinger, Christine, Wanschitz, Julia, Klimaschewski, Lars, Poewe, Werner, Stefanova, Nadia, Wenning, Gregor K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619736/
https://ncbi.nlm.nih.gov/pubmed/26496712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136575
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