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Molecular Analysis of the HOXA2-Dependent Degradation of RCHY1
The homeodomain transcription factor Hoxa2 interacts with the RING-finger type E3 ubiquitin ligase RCHY1 and induces its proteasomal degradation. In this work, we dissected this non-transcriptional activity of Hoxa2 at the molecular level. The Hoxa2-mediated decay of RCHY1 involves both the 19S and...
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| Publicado en: | PLoS One |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619689/ https://ncbi.nlm.nih.gov/pubmed/26496426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141347 |
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