Biomarkers of Endothelial Activation Are Associated with Poor Outcome in Critical Illness

BACKGROUND: Endothelial activation plays a role in organ dysfunction in the systemic inflammatory response syndrome (SIRS). Angiopoietin-1 (Ang-1) promotes vascular quiescence while angiopoietin-2 (Ang-2) mediates microvascular leak. Circulating levels of Ang-1 and Ang-2 in patients with SIRS could...

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Publicat a:PLoS One
Autors principals: Mikacenic, Carmen, Hahn, William O., Price, Brenda L., Harju-Baker, Susanna, Katz, Ronit, Kain, Kevin C., Himmelfarb, Jonathan, Liles, W. Conrad, Wurfel, Mark M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619633/
https://ncbi.nlm.nih.gov/pubmed/26492036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141251
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