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Mre11 and Blm-Dependent Formation of ALT-Like Telomeres in Ku-Deficient Ustilago maydis

A subset of human cancer cells uses a specialized, aberrant recombination pathway known as ALT to maintain telomeres, which in these cells are characterized by complex aberrations including length heterogeneity, high levels of unpaired C-strand, and accumulation of extra-chromosomal telomere repeats...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Yu, Eun Young, Pérez-Martín, José, Holloman, William K., Lue, Neal F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619612/
https://ncbi.nlm.nih.gov/pubmed/26492073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005570
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