Depletion of M. tuberculosis GlmU from Infected Murine Lungs Effects the Clearance of the Pathogen

M. tuberculosis N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU(Mtb)) is a bi-functional enzyme engaged in the synthesis of two metabolic intermediates N-acetylglucosamine-1-phosphate (GlcNAc-1-P) and UDP-GlcNAc, catalyzed by the C- and N-terminal domains respectively. UDP-GlcNAc is a key m...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Soni, Vijay, Upadhayay, Sandeep, Suryadevara, Priyanka, Samla, Ganesh, Singh, Archana, Yogeeswari, Perumal, Sriram, Dharmarajan, Nandicoori, Vinay Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619583/
https://ncbi.nlm.nih.gov/pubmed/26489015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005235
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