Whole genome sequencing reveals genomic heterogeneity and antibiotic purification in Mycobacterium tuberculosis isolates

BACKGROUND: Whole genome sequencing has revolutionised the interrogation of mycobacterial genomes. Recent studies have reported conflicting findings on the genomic stability of Mycobacterium tuberculosis during the evolution of drug resistance. In an age where whole genome sequencing is increasingly...

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Vydáno v:BMC Genomics
Hlavní autoři: Black, PA, de Vos, M., Louw, GE, van der Merwe, RG, Dippenaar, A., Streicher, EM, Abdallah, AM, Sampson, SL, Victor, TC, Dolby, T., Simpson, JA, van Helden, PD, Warren, RM, Pain, A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619333/
https://ncbi.nlm.nih.gov/pubmed/26496891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-2067-2
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