Loading...

Promiscuous Behavior of HPV16E6 Specific T Cell Receptor Beta Chains Hampers Functional Expression in TCR Transgenic T Cells, Which Can Be Restored in Part by Genetic Modification

Background: T cell receptor gene transfer is a promising strategy to treat patients suffering from HPV induced malignancies. Therefore we isolated the TCRαβ open reading frames of an HPV16E6 specific CTL clone and generated TCR transgenic T cells. In general low level expression of the transgenic TC...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Oncol
Main Authors: Scholten, Kirsten B. J., Ruizendaal, Janneke J., Graf, Marcus, Schoedl, Thomas, Kramer, Duco, Meijer, Chris J. L. M., Man, Stephen, Hooijberg, Erik
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619291/
https://ncbi.nlm.nih.gov/pubmed/20208133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0493
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!