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Three-Dimensional Microfluidic Tri-Culture Model of the Bone Marrow Microenvironment for Study of Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) initiates and progresses in the bone marrow, and as such, the marrow microenvironment is a critical regulatory component in development of this cancer. However, ALL studies were conducted mainly on flat plastic substrates, which do not recapitulate the characterist...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Bruce, Allison, Evans, Rebecca, Mezan, Ryan, Shi, Lin, Moses, Blake S., Martin, Karen H., Gibson, Laura F., Yang, Yong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619215/
https://ncbi.nlm.nih.gov/pubmed/26488876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140506
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