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Three-Dimensional Microfluidic Tri-Culture Model of the Bone Marrow Microenvironment for Study of Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia (ALL) initiates and progresses in the bone marrow, and as such, the marrow microenvironment is a critical regulatory component in development of this cancer. However, ALL studies were conducted mainly on flat plastic substrates, which do not recapitulate the characterist...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bruce, Allison, Evans, Rebecca, Mezan, Ryan, Shi, Lin, Moses, Blake S., Martin, Karen H., Gibson, Laura F., Yang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619215/
https://ncbi.nlm.nih.gov/pubmed/26488876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140506
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