Randomized phase II study of paclitaxel/carboplatin intercalated with gefitinib compared to paclitaxel/carboplatin alone for chemotherapy-naïve non-small cell lung cancer in a clinically selected population excluding patients with non-smoking adenocarcinoma or mutated EGFR

BACKGROUND: Considering cell cycle dependent cytotoxicity, intercalation of chemotherapy and epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) may be a treatment option in non-small cell lung cancer (NSCLC). This randomized phase 2 study compared the efficacy of paclitaxel and...

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Veröffentlicht in:BMC Cancer
Hauptverfasser: Choi, Yoon Ji, Lee, Dae Ho, Choi, Chang Min, Lee, Jung Shin, Lee, Seung Jin, Ahn, Jin-Hee, Kim, Sang-We
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619194/
https://ncbi.nlm.nih.gov/pubmed/26493267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1714-y
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